Isotonix Advanced B-Complex
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What Makes Isotonix Advanced B-Complex Unique?
Isotonix Advanced B-Complex is an isotonic-capable combination of the essential B vitamins with magnesium and potassium, which work synergistically to promote a myriad of health benefits and biological processes in the body. Isotonix Advanced B-Complex works to promote healthy red blood cell formation, increases energy, promotes cardiovascular health and helps maintain healthy levels of serotonin. B vitamins are necessary for proper functioning of the nervous system, bone marrow and muscle function. Vitamin B12 and folic acid facilitate steps required for cell division. Vitamin B5 is involved in the Krebs cycle of energy production and is needed to make the neurotransmitter acetylcholine as well as producing, transporting, and releasing energy from fats. Thiamin, riboflavin, niacin, and biotin participate in different aspects of energy production. The large amount of vitamin B12 provided in the Isotonix formula may be capable of forcing small amounts across the membranes of the intestines, this vitamin is carried into the body by forming a complex with Intrinsic Factor, a stomach derived protein. It enters the body bound to proteins, requiring an acidic pH level and proper pancreatic release of proteolytic enzymes. Because many vegetarian diets are lacking in the essential B-vitamins, Isotonix Advanced B-Complex meets the need for B-vitamins for vegetarians.
Isotonic, which means same pressure, bears the same chemical resemblance of the bodys blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The bodys common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be absorbed and used in the bodys metabolism, it must be transported in an isotonic state.
Isotonix dietary supplements are delivered in an isotonic solution. This means that the body has less work to do to in obtaining great absorption. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and be rapidly absorbed into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.
Related terms: Vitamin B12, B vitamins, energy
Primary Benefits of Isotonix Advanced B-Complex:
- Helps in the production of red blood cells and in treating anemia
- Aids in tissue formation and helps prevent neural tube defects when taken prior to becoming pregnant and during early pregnancy
- Contributes to the development and maintenance of bones and teeth, the maintenance of proper muscle function and helps the body to metabolize proteins, fats and carbohydrates to enhance energy production, and support cardiovascular health
Key Ingredients found in Isotonix Advanced B-Complex:
Cyanocobalamin (Vitamin B12)
Vitamin B12, a bacterial product is naturally found in organ meats, liver, beef, pork, eggs, whole milk, cheese, whole wheat bread and fish. B12 can only be found in animal products, with small amounts derived from the fermented soy products miso and peanuts. It is essential that vegetarians consume a Vitamin B12 supplement to maintain optimal health. Vitamin B12, when ingested, is stored in the liver and other tissues for later use. The synthetic form of B12, Cyanocobalamin, is not derived from either plants or animals and is intrinsic in the maintenance of normal functioning body cells, especially those of the nervous system (protecting the sheaths of nerve cells), bone marrow and intestinal tract. These tissues are first to exhibit signs of B12 depletion. Vitamin B12 itself is responsible for maintaining optimum energy levels, as it plays a vital role in the Krebs energy cycle.
Folate (Folic Acid)
Folic acid is mainly found in fruits and vegetables. Dark, leafy greens, oranges, orange juice, beans and peas are the best sources, as well as Brewers yeast, which supply additional B vitamins. Folic acid plays a key role by boosting the benefits of B12 supplementation. These two B vitamins join forces and work together in maintaining normal red blood cells. Folic acid assists in the normal utilization of amino acids and proteins as well as supporting the construction of the material for DNA and RNA synthesis. Scientific studies have found that when working in tandem with folic acid, B12 is capable of promoting normal homocysteine levels. This works toward supporting a healthy cardiovascular and nervous system.
Riboflavin 5-Phosphate (Vitamin B2)
Vitamin B2 is a found in liver, dairy products, dark green vegetables and some types of seafood. Vitamin B2 serves as a co-enzyme, working with other B vitamins. It promotes healthy red blood cell formation, supports the nervous system and normal human growth. It supports collagen growth and helps regulate thyroid activity. Vitamin B2 plays a crucial role in turning food into energy as a part of the electron transport chain, driving cellular energy on the micro-level. Riboflavin can be useful for pregnant or lactating women as well as athletes due to their higher caloric needs. Vitamin B2 aids in the breakdown of fats while functioning as a cofactor or helper in activating B6 and folic acid. Vitamin B2 is water-soluble and cannot be stored by the body except in insignificant amounts. It must be replenished daily.
Pyridoxine HCl (Vitamin B6)
Poultry, fish, whole grains and bananas are the main dietary sources of vitamin B6. B6 is a co-factor required for protein and amino acid metabolism and helps maintain proper fluid balance. It also assists in the maintenance of healthy red and white blood cells. B6 is required for hemoglobin synthesis. Vitamin B6 is involved in the synthesis of neurotransmitters in the brain and peripheral nerve cells and it supports nerve conduction. Some athletic supplements include vitamin B6 because it aids in the conversion of glycogen to glucose for energy in muscle tissue. Vitamin B6, when taken with folic acid, has been shown to help maintain normal plasma levels of homocysteine, which promotes optimal cardiovascular health. Vitamin B6 should be administered as a part of a complex of other B-vitamins for best results.
Foods rich in magnesium include unpolished grains, nuts and green vegetables. Green leafy vegetables are potent sources of magnesium because of their chlorophyll content. Meats, starches, milk, refined and processed foods contain low amounts of magnesium.
Magnesium is a component of the mineralized part of bone and is necessary for the metabolism of potassium and calcium in adults. It helps maintain normal levels of potassium, phosphorus, calcium, adrenaline and insulin. It is also important for transporting calcium inside the cell for utilization. Magnesium plays a key role in the functioning of muscle and nervous tissue and the synthesis of all proteins, nucleic acids, nucleotides, cyclic adenosine monophosphate, lipids and carbohydrates.
Magnesium is required for energy release, regulation of the body temperature, proper nerve function and regulating metabolism. Importantly, magnesium is also required by the body to build healthy bones, teeth, and normal muscle development. It works together with calcium and vitamin D to help keep bones strong. Magnesium, when combined with calcium, helps support the heart muscles in maintaining a regular heartbeat and promoting normal blood pressure.
Potassium is an electrolyte stored in the muscles. Foods rich in potassium include bananas, oranges, cantaloupe, avocado, raw spinach, cabbage and celery. Potassium is an essential macromineral that helps maintain fluid balance in the body. It also plays a role in a wide variety of biochemical and physiological processes. Among other things, potassium is important in the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, the synthesis of nucleic acids, and the maintenance of intracellular tonicity.
It also promotes glycogen and protein synthesis. Potassium is an electrolyte that promotes normal heartbeat. Potassium is important in releasing energy from protein, fat, and carbohydrates during metabolism. Potassium helps regulates water balance, aids in recovery from exercise and helps with the elimination of wastes. Sodium and potassium are two of the most important ions in maintaining the homeostatic equilibrium of the body fluids.
Thiamin HCl (Vitamin B1)
Thiamin plays an important role in carbohydrate metabolism and nerve function. Thiamin is required for a healthy nervous system and assists in the production of the neurotransmitter acetylcholine and gamma-aminobutyric acid (GABA). It is also used in the manufacture of hydrochloric acid.
D-Calcium Pantothenate (Vitamin B5)
Pantothenic acid (B5) is the transfer agent for Choline to acetylcholine, which aids in proper neurotransmitter activity in the brain. Pantothenic acid is also known as the anti-stress vitamin. It also plays very important role in the secretion of hormones.
Niacinamide (Vitamin B3)
Niacin is a water-soluble vitamin necessary for many aspects of health, growth and reproduction. It is part of the vitamin B complex. Niacin assists in the functioning of the digestive system, skin and nerves. It is also important for the conversion of food to energy. Niacin (also known as vitamin B-3) is found in dairy products, poultry, fish, lean meats, nuts and eggs, as well as legumes and enriched breads and cereals.*
Biotin (Vitamin B7)
Biotin can be found in food sources such as egg yolks, peanuts, beef liver, milk (10 mcg/cup), cereals, almonds and Brewers yeast. Biotin is used in healthy cell growth, the production of fatty acids, metabolism of fats, and amino acids. It plays a role in the Citric acid cycle, which is the process in which biochemical energy is generated during aerobic respiration. Biotin not only assists in various metabolic chemical conversions, but also helps to transfer carbon dioxide.
Frequently Asked Questions about Isotonix Advanced B-Complex:
What is Isotonix Advanced B-Complex?
Isotonix Advanced B-Complex is a blend of all B-vitamins with potassium and biotin. Because of the isotonic state of this blend, one can be sure that the maximum amounts of nutrients are reaching their target areas with utmost efficiency. An isotonic solution is one that actually matches the bodys own osmolarity and is easily absorbed into ones system. Other isotonic solutions of the body include tears, plasma and mothers milk. These all-star B-vitamins join in the proper amounts for maximal utilization and absorption. B12 and the other B vitamins act as members of a team. When taken all together, B12 acts as a key player in the production of energy, cell maintenance and promotion of normal nervous system functioning. Folic acid is also present, playing an integral role in aiding B12 in the healthy utilization of amino acids and proteins as well as DNA and RNA synthesis.
What is the source of the vitamin B12 in our Isotonix Advanced B-Complex?
Vitamin B12 is a bacterial product, not synthesized by plants or animals. We get it by taking supplements or by eating eggs or meats. Vegetarians are recommended to take a B vitamin dietary supplement.
Can a person who lacks Intrinsic Factor and has to take B12 shots get benefits from taking Isotonix Advanced B-Complex?
No. Vitamin B12 requires intrinsic factor, a B12 binding protein synthesized in stomach parietal cells for proper absorption.
Why are B-vitamins so important in the aging process?
The ability to absorb B-vitamins naturally decreases with age, and various indicators of cognitive impairment are associated with reduced B-vitamin levels. The elderly in general suffer from a reduction in sense of taste and thus appetite and may use many acid reducing medicines that predispose them to B12 deficiency. According to Robert M. Russell of the U.S. RDAs
I am young and healthy. Why should I take Advanced B-Complex?
Health experts estimate that one in five adults is deficient in one of the B-vitamins. Absorption of vitamin B12 is a complex process, which can lead to B12 deficiency. Keep in mind that even in a healthy persons gastrointestinal tract, there are always other proteins and vitamins competing for absorption alongside vitamin B12, which is so large and complex that it very often must struggle for entrance into the bloodstream. Specifically at risk for deficiency are vegetarians, heavy drinkers, those who take a lot of prescription or over-the-counter drugs, those with digestive disorders, pernicious anemia, recipients of gastric bypass surgery and those with poor diets. A vitamin B-complex is great for athletes, especially endurance athletes who need a natural boost of energy before a workout, due to its beneficial effects promoting the oxygenation of red blood cells.*
Is it toxic to take too much vitamin B12?
Studies have found no confirmed reports of toxic side effects from heightened dosages of vitamin B12. However, you should only take Isotonix Advanced B-Complex as directed on the bottle.*
Are there any warnings or contraindications for Isotonix Advanced B-Complex?
No. Isotonix B-Complex is a vegetarian product and contains no wheat, gluten, soy, yeast, artificial flavor, starch, salt, preservatives or milk.
How do I take Isotonix Advanced B-Complex?
Pour one (1) level bottle capful of powder into the overcap. Add water to the line on the overcap (60 ml/2 fl. oz.). This product is best when taken with a meal. This product is isotonic only if the specified amounts of powder and water are used.
Scientific Support for Isotonix Advanced B-Complex:
· Benton D., et al. Thiamine supplementation for mood and cognitive functioning. Psychopharmacology. 129(1):66-71, 1997.
· Benton, D., et al. The effects of nutrients on mood. Public Health Nutr. 2(3A):403-409, 1999.
· Bhagavan, H. N., et al. The effect of pyridoxine hydrochloride on blood serotonin and pyridoxal phosphate contents in hyperactive children. Pediatrics. 55(3):437-441, 1975.
· Bronstrup A, Hages M, Prinz-Langenohl R, Pietrzik K. Effects of folic acid and
· Bryan, J., et al. Associations between dietary intake of folate and vitamins B-12 and B-6 and self-reported cognitive function and psychological well-being in Australian men and women in midlife. J Nutr Health Aging. 8(4):226-232, 2004.
· Bryan, J., et al. Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages. Journal of Nutrition. 132(6):1345-1356, 2002.
· combinations of folic acid and vitamin B12 on plasma homocysteine concentrations in healthy young women. Am J Clin Nutr 68:1104-10, 1998.
· Coppen, A., et al. Plasma folate and affective morbidity during long-term lithium therapy. Br J Psychiatry. 141:87-89, 1982.
· Cummings, P. M., et al. Effect of folic acid and antioxidant vitamins on endothelial dysfunction in patients with coronary artery disease. J Am Coll Cardiol. 36:758-765, 2000.
· Dharmarajan, T. S., et al. Vitamin B12 deficiency. Recognizing subtle symptoms in older adults. Geriatrics. 58(3):30-34, 2003.
· Doshi, S. N., et al. Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering. Circulation. 105(1):22-26, 2002.
· Duthie, S. J., et al. Homocysteine, B vitamin status, and cognitive function in the elderly. American Journal of Clinical Nutrition. 75(5):908-913, 2002.
· Friso, S., et al. Low plasma vitamin B-6 concentrations and modulation of coronary artery disease risk. Am J Clin Nutr. 79(6):992-998, 2004.
· Grant, J. E., et al. Analysis of dietary intake and selected nutrient concentrations in patients with chronic fatigue syndrome. J Am Diet Assoc. 96(4):383-386, 1996.
· Hartvig, P., et al. Pyridoxine effect on synthesis rate of serotonin in the monkey brain measured with position emission tomography. Neural Trans. 102:91-97, 1995.
· Heap, L. C., et al. Vitamin B status in patients with chronic fatigue syndrome. J R Soc Med. 92(4):183-185, 1999.
· Heseker, H., et al. Psychological disorders as early symptoms of a mild-to-moderate vitamin deficiency. Ann N Y Acad Sci. 669:352-357, 1992.
· Jacobson, W., et al. Serum folate and chronic fatigue syndrome. Neurology. 43:2645-2647, 1993.
· Kelly, G. S. Nutritional and botanical interventions to assist with the adaptation to stress. Alternative Medicine Review.4(4):249-265, 1999.
· Litoff, D., et al. Effects of pantothenic acid supplementation on human exercise. Med Sci Sport Exercise., 17(Supplement):287, 1985.
· Osada, K., et al. Experimental study of fatigue provoked by biotin deficiency in mice. Int J Vitam Nutr Res. 74(5):334-340, 2004.
· Quadri, P., et al. Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia. Am J Clin Nutr. 80(1):114-122, 2004.
· Riggs, K. M., et al. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. American Journal of Clinical Nutrition. 63(3):306-314, 1996.
· Van den Berg M., et al. Combined vitamin B-6 plus folic acid therapy in young patients with arteriosclerosis and hyperhomocysteinemia. Journal Vascular Surgery. 20(6):933-940, 1994.
· van Oort FV, Melse-Boonstra A, Brouwer IA, et al. Folic acid and reduction of plasma homocysteine concentrations in older adults: a dose-response study. 77:1318-23, 2003.
· Vargiu, R., et al. Enhancement of muscular performance by a coformulation of propionyl-L-carnitine, coenzyme Q(10), nicotinamide, riboflavin and pantothenic acid in the rat. Physiol Behav. 76(2):257-63, 2002.
· Wald DS, Bishop L, Wald NJ, et al. Randomized trial of folic acid supplementation and serum homocysteine levels. Arch Intern Med 61:695-700, 2001.
· Werbach, M. R. Nutritional strategies for treating chronic fatigue syndrome. Alternative Medicine Review. 5(2):93-108, 2000.
· Woo, K. S., et al. Long-term improvement in homocysteine levels and arterial endothelial function after 1-year folic acid supplementation. American Journal of Medicine. 112(7):535-539, 2002.
In the News:
The Importance of the B12 Vitamin
By Tony Luck
Vegetarian Source of Vitamin B12
By: Alan R. Gaby
SOURCES: Townsend Letter for Doctors and Patients, May 2003 p32(1)
Vegetarian source of vitamin B12.
Looking for a Memory Pill?
By: Holly McCord, RD
Source: Amer. Jour. of Clinical Nutrition, Feb 2000.
Vegetarian and Pregnant?
By: Gloria McVeigh
Source: Prevention Nutrition News Editor, 2006
B Vitamins to
Source: Decision News © Copyright DecisionNewsMedia SAS 2006
Stroke and Broken Bones
By: Elizabeth Querna
Vitamin B6, B12 and Folic Acid: Provocative New Findings
New Research on B Vitamins' Possible Relationship to Cognitive Health and Blood Sugar
By:Karen Kaufman, MS, CCN
*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.